No. However, uninstall at the machine, then reinstall seemed to get things working.
Windows Registry Editor Version 5.00
[HKEY_LOCAL_MACHINE\SOFTWARE\Red Gate]
[HKEY_LOCAL_MACHINE\SOFTWARE\Red Gate\SQL Backup]
[HKEY_LOCAL_MACHINE\SOFTWARE\Red Gate\SQL Backup\BackupSettings]
[HKEY_LOCAL_MACHINE\SOFTWARE\Red Gate\SQL Backup\BackupSettings\(LOCAL)]
[HKEY_LOCAL_MACHINE\SOFTWARE\Red Gate\SQL Backup\BackupSettings\LOCALDEV]
[HKEY_LOCAL_MACHINE\SOFTWARE\Red Gate\SQL Backup\BackupSettingsGlobal]
[HKEY_LOCAL_MACHINE\SOFTWARE\Red Gate\SQL Backup\BackupSettingsGlobal\(LOCAL)]
"DataPath"="C:\\ProgramData\\Red Gate\\SQL Backup\\Data\\(local)"
"LogFolder"="C:\\ProgramData\\Red Gate\\SQL Backup\\Log\\(local)"
"ServiceLogin"=""
"CopiedVersion4Settings"=dword:00000001
"Copied32BitSettings"=dword:00000001
"SkipChecks"=dword:00000001
[HKEY_LOCAL_MACHINE\SOFTWARE\Red Gate\SQL Backup\BackupSettingsGlobal\LOCALDEV]
"DataPath"="C:\\ProgramData\\Red Gate\\SQL Backup\\Data\\LOCALDEV"
"LogFolder"="C:\\ProgramData\\Red Gate\\SQL Backup\\Log\\LOCALDEV"
"ServiceLogin"=""
"CopiedVersion4Settings"=dword:00000001
"Copied32BitSettings"=dword:00000001
"SkipChecks"=dword:00000001
[HKEY_LOCAL_MACHINE\SOFTWARE\Red Gate\SQL Backup\InstalledInstances]
[HKEY_LOCAL_MACHINE\SOFTWARE\Red Gate\SQL Backup\InstalledInstances\(LOCAL)]
[HKEY_LOCAL_MACHINE\SOFTWARE\Red Gate\SQL Backup\InstalledInstances\LOCALDEV]
Windows Registry Editor Version 5.00
[HKEY_LOCAL_MACHINE\SOFTWARE\Red Gate]
[HKEY_LOCAL_MACHINE\SOFTWARE\Red Gate\SQL Backup]
[HKEY_LOCAL_MACHINE\SOFTWARE\Red Gate\SQL Backup\BackupSettings]
[HKEY_LOCAL_MACHINE\SOFTWARE\Red Gate\SQL Backup\BackupSettings\(LOCAL)]
[HKEY_LOCAL_MACHINE\SOFTWARE\Red Gate\SQL Backup\BackupSettings\LOCALDEV]
[HKEY_LOCAL_MACHINE\SOFTWARE\Red Gate\SQL Backup\BackupSettingsGlobal]
[HKEY_LOCAL_MACHINE\SOFTWARE\Red Gate\SQL Backup\BackupSettingsGlobal\(LOCAL)]
"DataPath"="C:\\ProgramData\\Red Gate\\SQL Backup\\Data\\(local)"
"LogFolder"="C:\\ProgramData\\Red Gate\\SQL Backup\\Log\\(local)"
"ServiceLogin"=""
"CopiedVersion4Settings"=dword:00000001
"Copied32BitSettings"=dword:00000001
"SkipChecks"=dword:00000001
[HKEY_LOCAL_MACHINE\SOFTWARE\Red Gate\SQL Backup\BackupSettingsGlobal\LOCALDEV]
"DataPath"="C:\\ProgramData\\Red Gate\\SQL Backup\\Data\\LOCALDEV"
"LogFolder"="C:\\ProgramData\\Red Gate\\SQL Backup\\Log\\LOCALDEV"
"ServiceLogin"=""
"CopiedVersion4Settings"=dword:00000001
"Copied32BitSettings"=dword:00000001
"SkipChecks"=dword:00000001
[HKEY_LOCAL_MACHINE\SOFTWARE\Red Gate\SQL Backup\InstalledInstances]
[HKEY_LOCAL_MACHINE\SOFTWARE\Red Gate\SQL Backup\InstalledInstances\(LOCAL)]
[HKEY_LOCAL_MACHINE\SOFTWARE\Red Gate\SQL Backup\InstalledInstances\LOCALDEV]